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  • Know Res., 2015, 2(3),  pp 124-130  

    DOI:10.7598/kor2015.134

    Research Article

    A Convenient Method for One-Pot Synthesis of β-Acetamido Ketones using Nano-Alumina Sulfuric Acid (Nano-ASA) Reusable Catalyst

  • ALI GHARIB1,2*, LEILA VOJDANI FARD3, NADER NOROOZI PESYAN4, MANOUCHEHR JAHANGIR1 and MINA ROSHANI1
  • 1Department of Chemistry, Islamic Azad University, Mashhad, Iran
    2Agricultural Researches and Services Center, Mashhad, Iran
    3Education Ministry, Education Organization of Razavi Khorasan, Mashhad, Iran
    4Department of Chemistry, Faculty of Science, Urmia University, 57159 Urmia, Iran
  • Abstract

    We describe an efficient method for the synthesis of β-acetamido ketones through the condensation of an aryl(aromatic) aldehyde, an acetophenone, acetyl chloride, and acetonitrile in the presence of natural alumina, alumina sulfuric acid (ASA), nano- γ -alumina, nano alumina sulfuric acid (nano-ASA) at room temperature. High efficiency, easy availability and reusability are some advantages of nano alumina sulfuric acid (nano-ASA) catalyst.

    Keywords

    Nano-γ -alumina, Nano-alumina sulfuric acid, Synthesis, β-acetamido carbonyl compounds, Re

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