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  • Know Res., 2015, 2(4),  pp 154-158  

    DOI:10.7598/kor2015.161

    Research Article

    Essential Oil Constituents and its Antimicrobial Activity of Agastache rugosa (Fisch. et Mey) from Xinjiang, China

  • HAIYAN GONG1,2, YU WANG2, SHUGE TIAN2 and CHEN ZHANG1* YU WANG 2, SHUGE TIAN and CHEN ZHANG
  • 1The Fifth Affiliated Hospital of Xinjiang Medical, Urumqi-830054, Xinjiang, PR China
    2Xinjiang Medical University, Urumqi-830054, Xinjiang, PR China
  • Abstract

    The study was conducted to evaluate the constituents and antimicrobial activity of essential oils from Agastache rugosa collected in Xinjiang. Using GC and GCMS analysis, essential oil of flower (EOF) was revealed the presence of twenty-one components, representing 99.78% of the total oil, which major compounds were pulegone (34.1%) followed by estragole (29.5%), p-Menthan-3-one (19.2%). Twenty-six components accounting for 99.62% of constituents from essential oil of leaf (EOL) were identified, the major compounds were p-Menthan-3-one (48.8%) and estragole (20.8%). The EOF showed strong inhibition against Staphylococcus aureus and Escherichia coli; strong inhibition against Escherichia coli of EOL. There is a very effective antimicrobial activity with Minimum Inhibitory Concentration (MIC) ranging from 9.4-42 µgmL-1.

    Keywords

    Agastache rugosa; essential oil; GCMS; antimicrobial activity

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